Hello Giancarlo,
Many thanks for all your help. You rock it!
The rule you suggested it's working perfectly with a minimal change.
This is the definitively used rule set, in case it may help someone else.
-----------------------------------------------------------
###############################################################################
## FILTER: Routing outgoing to ISP2
###############################################################################
pass in quick on $dmz_if from $dmz_net to $lan_net
pass in quick on $dmz_if route-to ($isp2_if $isp2_gw) \
from $dmz_net to !$lan_net
pass in on $isp2_if reply-to ($isp2_if $isp2_gw) proto {tcp udp} \
from any to $srv_web_001 port {http https}
-----------------------------------------------------------
Once again, thanks you Giancarlo.
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